Relative timing between kappa opioid receptor activation and cocaine determines the impact on reward and dopamine release

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Chartoff EH, Ebner SR, Sparrow A, Potter D, Baker PM, Ragozzino ME, Roitman MF (2016) Neuropsychopharmacology

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A descending dopamine pathway conserved from basal vertebrates to mammals
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Physiological state gates acquisition and expression of mesolimbic reward prediction signals